The role of oculomotor mechanisms in the control of spatial attention
by Fallah, Mazyar, Ph.D.,
Princeton University, 2001, 119 pages; AAT 3007213
Spatial attention is the ability to preferentially process one portion of the visual field without moving the eyes. The neural mechanisms underlying spatial attention are currently unknown. Imaging studies, however, have shown a fronto-parietal network activated during spatial attention tasks. One common feature of these activated areas is that each is also involved in the control of eye movements.
We set out to directly test the relationship between oculomotor mechanisms and spatial attention, by electrically stimulating neurons in the frontal eye fields (FEF), a cortical area in the frontal lobe, and measuring its effects on spatial attention. Electrical stimulation of a specific site in FEF can initiate saccadic eye movements. The termination points of the stimulation evoked saccades cluster within a region of the visual field, called the motor field of the site. The psychophysical threshold for detecting a transient luminance decrement in a visual target was measured with and without microstimulation at currents below the levels that initiate saccades.
The results showed that subthreshold stimulation of a specific site within FEF significantly improved the monkeys' ability to detect a transient luminance decrement change when the target was placed within the site's motor field. By contrast, when the target was placed outside of the motor field, stimulation did not improve the thresholds for detection. Thus, there was a spatial extent to the facilitation effect of microstimulation.
There was also a temporal extent to the effect of microstimulation on spatial attention. When the microstimulation occurred within 175 ms prior to the luminance decrement, facilitation was observed inside, but not outside, the motor field. In contrast, at longer temporal intervals, there was no effect of microstimulation either inside or outside the motor field.
In summary, the results show that oculomotor mechanisms can modulate spatial attention. These are the first results to show a causal relationship between oculomotor mechanisms and spatial attention. Spatial attention mechanisms and oculomotor mechanisms appear to share common neural mechanisms.